Fundings - Current projects
2019-2024 | Searching for structure – antimicrobial activity correlation for selected boraheterocycles
Narodowe Centrum Nauki, OPUS 16, Grant No. UMO- 2018/31/B/ST5/00210
The project deals with the synthesis and characterization of selected groups of heterocyclic compounds bearing the boron atom. It is focused on emerging systems such as benzosiloxaboroles, benzophosphoxaboroles and benzoxadiboroles. In all these compounds the boraheterocycle featuring the B-O-El linkage (El = Si, P, B) is fused with aromatic or heteroaromatic ring. The most important part of the project deals with the evaluation of the activity of obtained compounds as agents possessing a direct antimicrobial (antibacterial and antifungal) activity or as beta-lactamase inhibitors for use in combination with beta-lactam antibiotics for the treatment of Gram-negative bacilli infections. Moreover, the aim of this part of the research is the prevention of single-step resistant mutant selection leading to reduced bacterial sensitivity to the new compounds and characterization the selected mutants.
Donation: 425 600$,
PI: Sergiusz Luliński
Consortium grant with Medicinal University of Warsaw
2021-2024 | Efficient triplet photosensitizers derived from rigid organoboron structures as singlet oxygen generators
Narodowe Centrum Nauki, OPUS 20, Grant No. UMO-2020/39/B/ST4/02370
Inspired by the challenges encountered in the field of triplet state photosensitizers I propose to undertake interdisciplinary research for development of new generation triplet photosensitizers that are based on rigid organoboron complexes. It represents a novel approach because it goes beyond the common scheme for molecular structure modifications of boroorganic compounds. My initial studies clearly show that the spiro-boron architecture with annulated semi-rigid organoboron core promotes hidden and previously overlooked triplet-state functionality of organoboron dyes. More importantly, this effect is not restricted to any particular type of organoboron complex such BODIPY and thus leads to thousands new possible triplet state photosensitizers. The modular construction of boron complexes enables fine modification of both organoboron and ligand parts that can be exploited for the development of new generation of photocatalysts and antimicrobial agents. Furthermore, proposed strategy can be easily combined with other already developed ones (e.g. insertion of heavy-atom). Consequently, the project aims at the development of various spiro-boracyclic triplet state photosensitizers and utilization of their potential application as singlet oxygen generators for organic chemistry, medicine and water purification..
Donation: 330 000$,
PI: Krzysztof Durka
2020-2024 | THIO-SWITCH: towards novel photo-active switchable materials - exploration of dithienylethene-based transition-metal complexes via advanced in situ photocrystallographic and spectroscopic approaches
Narodowe Centrum Nauki, OPUS 17, Grant No. UMO- 2019/33/B/ST4/03144
We concentrate on systems in which the molecule contains the dithienylethene (DTE) fragment that can work as two-direction switch using light of various wavelengths (DTE core can be found in two forms – open and closed – which can be transformed one into another). Such switching is often accompanied by the material’s colour changes or other properties (e.g. luminescence decay). The aim of our project is to better understand the switching process in transition-metal complexes containing the DTE group.
Years: 2020-2023
PI: Radosław Kamiński (WU) / Krzysztof Durka (WUT)
Consortium grant with Warsaw University
Finished projects
2020-2021 | Effective triplet-state photosensitizers based on four-coordinated spiro organoboron complexes immobilized on the solid state surface.
Warsaw University of Technology, POB-TM1
The aim of this project is to synthesise new types of singlet-oxygen photosensitizers derived from spiro-boracyclic semi-rigid complexes and their immobilization on solid-state materials.
Years: 2020-2021
PI: Krzysztof Durka
2019-2021 | Structure of chiral motif vs. spontaneous enantiomer crystallization - a case of lithium halides and biogenic amino-acids ionic co-crystals
Narodowe Centrum Nauki, PRELUDIUM 15, Grant No. UMO- 2018/29/N/ST4/00451
The aim of this project is to recognize and describe structural factors responsible for creating chiral motives in ionic co-crystal structures. This is to be achieved by obtaining well-defined consistent data-set, so called “structural library”, of ionic co-crystals composed of lithium halides and biogenic amino-acids of different chirality, and further meticulous analysis of the crystal structures supported by quantum-chemical calculations.
Years: 2019-2021
Donation: 210 000 PLN,
PI: Paulina Marek
2021 |Boroorganiczne związki fotoaktywne do zastosowań w chemii materiałowej i katalizie
Grant rektorski, Flogiston, Grant No. 1820/117/Z16/2021
Year: 2021
Donation: 32 000 PLN,
PI: Krzysztof Durka
2016-2019 | Covalent and hybrid porous materials based on organoboron compounds
Polish National Centre of Science grant “Opus” (Grant No. 2016/19/D/ST5/007352).
The project is primarily aimed at the design of novel functional materials featuring porous structure capable of storage or separation of technically and environmentally important gases.
Donation: 160 000$
PI: Sergiusz Luliński
2015-2019 | Four-coordinate organoboron complexes with rigid scaffolds as efficient light-emitting materials
Polish National Centre of Science grant “Sonata” (Grant No. 2015/19/D/ST5/007352).
The project was focused on the synthesis and characterization of luminescence complexes based on rigid organoboron core and selected (N,O), (N,N), (N,C) ligands.
Donation: 140 000$
PI: Krzysztof Durka
2012-2015 | Bimetallic compounds derived from heteroarylboranes – new attractive building blocks for organic synthesis and material chemistry
Polish National Centre of Science grant (Grant No. 2011/03/B/ST5/02755).
The project was focused on the synthesis and characterization of heteroaromatic bimetallic compounds, with a special emphasis on thiophene, furan and pyridine derivatives.
Results: 11 scientific publications.
PI: Sergiusz Luliński
2011-2013 | Aryl- and heteroaryldiboronic acids as synthons in the construction of supramolecular materials and potential gas storage materials.
Polish National Centre of Science grant “Sonata” (Grant No. 2015/19/D/ST5/007352).
The aim of this project was to synthesize multiboronic acids based on heteroaromatic cores which could serve as building blocks for the construction of polymeric materials. (2011-2013).
Results: 2 scientific publications - (a) Tetrahedron, 2013, 69, 3159−3166; (b) Organometallics, 33, 2014, 1608−1616;
PI: Krzysztof Durka
2011-2013 | From simple molecules of diboronic acid derivatives to tunable organoboron functional supramolecular complexes
Polish National Centre of Science grant “Preludium” (Grant No. 2011/01/N/ST5/05592).
he aim of this project was to synthesize tunable functional supramolecular or/and host-guest complexes based on phenylenediboronic acid derivatives..
Results: 3 scientific publications - (a) Eur. J. Org. Chem., 2012, 2208-2218; (b) Cryst. Growth Des., 2013, 13, 4181-4185; (c) Cryst. Growth Des., 2012, 12, 3720-3724.
PI: Krzysztof Durka
2015-2019 | Four-coordinate organoboron complexes with rigid scaffolds as efficient light-emitting materials
Polish National Centre of Science grant “Sonata” (Grant No. 2015/19/D/ST5/007352).
The project was focused on the synthesis and characterization of luminescence complexes based on rigid organoboron core and selected (N,O), (N,N), (N,C) ligands.
Donation: 140 000$
PI: Krzysztof Durka
2016-2019 | Covalent and hybrid porous materials based on organoboron compounds
Polish National Centre of Science grant “Opus” (Grant No. 2016/19/D/ST5/007352).
The project is primarily aimed at the design of novel functional materials featuring porous structure capable of storage or separation of technically and environmentally important gases.
Donation: 160 000$
PI: Sergiusz Luliński
2011-2013 | Aryl- and heteroaryldiboronic acids as synthons in the construction of supramolecular materials and potential gas storage materials.
Polish National Centre of Science grant “Sonata” (Grant No. 2015/19/D/ST5/007352).
The aim of this project was to synthesize multiboronic acids based on heteroaromatic cores which could serve as building blocks for the construction of polymeric materials. (2011-2013).
Results: 2 scientific publications - (a) Tetrahedron, 2013, 69, 3159−3166; (b) Organometallics, 33, 2014, 1608−1616;
PI: Krzysztof Durka
2012-2015 | Bimetallic compounds derived from heteroarylboranes – new attractive building blocks for organic synthesis and material chemistry
Polish National Centre of Science grant (Grant No. 2011/03/B/ST5/02755).
The project was focused on the synthesis and characterization of heteroaromatic bimetallic compounds, with a special emphasis on thiophene, furan and pyridine derivatives.
Results: 11 scientific publications.
PI: Sergiusz Luliński
2011-2013 | From simple molecules of diboronic acid derivatives to tunable organoboron functional supramolecular complexes
Polish National Centre of Science grant “Preludium” (Grant No. 2011/01/N/ST5/05592).
he aim of this project was to synthesize tunable functional supramolecular or/and host-guest complexes based on phenylenediboronic acid derivatives..
Results: 3 scientific publications - (a) Eur. J. Org. Chem., 2012, 2208-2218; (b) Cryst. Growth Des., 2013, 13, 4181-4185; (c) Cryst. Growth Des., 2012, 12, 3720-3724.
PI: Krzysztof Durka
Faculty of Chemistry
Warsaw University of Technology
Department of Physical Chemistry
Noakowskiego 3
00-664 Warsaw, Poland
Prof. Sergiusz Luliński
phone: +48 22 234 7273